Anti-FLT4 antibody produced in rabbit, affinity isolated antibody

Not available outside of the UK & Ireland.

Application

Anti-FLT4 antibody produced in rabbit has been used in immunohistochemistry.

Biochem/physiol Actions

Fms related tyrosine kinase 4 (FLT4) has a role in lymphangiogenesis and angiogenesis. It acts as an activator in signaling pathways. Mutations in the gene encoding FLT4 have been linked to Milroy disease.

Disclaimer

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Features and Benefits

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General description

Fms related tyrosine kinase 4 (FLT4) is also known as vascular endothelial growth factor receptor 3 (VEGFR3). It is expressed in the blood and lymphatic endothelial cells during early development. The gene encoding FLT4 is localized on human chromosome 5q35.3.

Immunogen

Peptide sequence around aa. 1279-1283 (L-A-S-E-E), according to the protein FLT4.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Target description

Receptor for VEGFC. Has a tyrosine-protein kinase activity.