Anti-TRPC6 antibody produced in rabbit, affinity isolated antibody

Not available outside of the UK & Ireland.

Disclaimer

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Features and Benefits

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Immunogen

peptide Corresponding to the amino terminal sequence from mouse TRPC6 protein , according to the protein TRPC6.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Target description

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).