Not available outside of the UK & Ireland.
Features and Benefits
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Immunogen
Peptide sequence around aa. 110-114 or 92-96 (D-L-S-P-L), according to the protein ATF2.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
Target description
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
This product has met the following criteria to qualify for the following awards: