Anti-ATF2 (Ab-62 or 44) antibody produced in rabbit, affinity isolated antibody

Not available outside of the UK & Ireland.

Features and Benefits

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Immunogen

Peptide sequence around aa. serine 60-64 or 42-46 (N-D-S-V-I), according to the protein ATF2.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Target description

Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.