Anti-phospho-KIT (pTyr721) antibody produced in rabbit, affinity isolated antibody

Not available outside of the UK & Ireland.

Features and Benefits

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Immunogen

Peptide sequence around phosphorylation site of tyrosine 721 (N-E-Y(p)-M-D)., according to the protein KIT.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Target description

This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K).