Anti-TMEM214 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution, ab2

Not available outside of the UK & Ireland.

Features and Benefits

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Immunogen

TMEM214 antibody was raised against a 17 amino acid peptide near the center of human TMEM214.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500086.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Target description

Transmembrane protein 214 (TMEM214) is a 77kD membrane protein which is widely expressed at high level. The gene encoding this protein maps to chromosome 2, at 2p23.3 TMEM214 interacts with LSM1, an SM-like protein, forming a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. The detailed function of TMEM214 is still unknown, but a recent study showed that TMEM214 may be used to explore the contribution of human host factors of some infectious diseases such as Dengue fever, West Nile fever and yellow fever. Multiple isoforms of TMEM214 are known to exist.