Monoclonal Anti-RPA3 antibody produced in mouse,

Not available outside of the UK & Ireland.

Application

For IP: Use at a concentration of 0.1 - 2 µg/mL. For WB: Use at a concentration of 0.1 - 2 µg/mL. For IHC-P: 1:100-1:1000. Predicted molecular weight: 14 kDa. Optimal dilutions/concentrations should be determined by the researcher.

Biochem/physiol Actions

Replication protein A (RPA) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32 and 14 kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. RPA has been shown to be a target for DNA-dependent protein kinase (DNA-PK) ataxia telangiectasia-mutated gene (ATM) and a cyclin dependent protein kinase.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Immunogen

Full-length human RPA-14 expressed in E. coli..

Physical form

Phosphate-buffered saline, no preservative added.