Anti-IDO2 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Indoleamine 2,3 dioxygenase (IDO) 2 plays an important role in the metabolism of tryptophan and in immune regulation. It may participate in B cell-mediated autoimmune diseases. IDO2 is required for IDO1-dependent induction of T regulatory cells (Treg). Removal of IDO2 results in attenuated contact hypersensitivity (CHS) responses.

Disclaimer

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Features and Benefits

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General description

Indoleamine 2,3 dioxygenase (IDO) 2 is one of the four tryptophan catabolic enzymes in mammals. IDO2 is located on human chromosome 8p21.

Immunogen

Peptide with sequence CRDKTLESILHPR, from the C-Terminus of the protein sequence according to NP_919270.2.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.