ANTI-FEM1A (C-TERMINAL)

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Fem-1 homolog A (FEM1A) is a substrate recognition subunit of cullin-2-RING E3 ubiquitin ligase complex. It has a role in the degradation of stem-loop binding protein (SLBP) and may be involved in anti-inflammatory signaling. FEM1A has been associated with polycystic ovary syndrome.

Features and Benefits

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General description

Fem-1 homolog A (FEM1A) is a homolog of the Fem-1 gene of Caenorhabditis elegans. It is predicted to encode an ankyrin repeat proteins which is expressed in many tissues. FEM1A is a conserved VHL-box protein. The gene encoding it is localized on human chromosome 19p13.3.

Immunogen

Peptide with sequence CGFIPEDLEAFIELH, from the C Terminus of the protein sequence according to NP_061178.1.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.