Anti-GATA1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

GATA binding protein 1 (GATA1) plays a crucial role in erythroid and megakaryocyte differentiation and proliferation. It modulates the expression of genes and acts as an E-cadherin repressor. Mutations in the GATA1 gene have been linked to transient abnormal myelopoiesis (TAM) and myeloid leukemia of DS (ML-DS). The protein has anti-apoptotic functions in breast cancer.

Features and Benefits

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General description

GATA binding protein 1 (GATA1) is a key hematopoietic transcription factor. It is part of the GATA transcription factor family and the gene encoding it is localized on human chromosome Xp11.23.

Immunogen

Peptide with sequence C-DAEAYRHSPVFQ from the internal region of the protein sequence according to NP_002040.1.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.