Anti-FTL antibody produced in goat, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Anti-FTL antibody produced in goat has been used in western blotting (1:500).

Biochem/physiol Actions

Ferritin light (FTL) subunit is an important protein in iron metabolism but lacks catalytic activity. This protein participates in the nucleation and mineralization of the iron center. FTL acts as a biomarker to differentiate between malignant and benign tumors. Overexpression of the FTL gene is observed in several malignant tumors and plays an important role in mediating the malignancy of cancers. FTL gene plays a role in the pathogenesis of glioblastoma. Mutation or deletion of the FTL gene is associated with neuroferritinopathy.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Ferritin light (FTL) subunit along with ferritin heavy (FTH) subunit are members of the ferritin complex. FTL gene is mapped on the human chromosome at 19q13.33.

Immunogen

Peptide with sequence C-GEYLFERLTLKHD from the C Terminus of the protein sequence according to NP_000137.2.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.