Anti-EXOC7 antibody produced in goat, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Anti-EXOC7 antibody produced in goat is suitable for immunohistochemistry, indirect ELISA, and western blot analysis.

Biochem/physiol Actions

EXOC7 (Exocyst complex component 7) is mainly involved in the exocytosis, a membrane trafficking process of intracellular protein elements such as hormones and neurotransmitters, membrane proteins and lipids to specific domains of the plasma membrane. Exocytosis plays a vital role in the cellular growth, development and cell polarity establishment. During exocytosis, it directly connects with the plasma membrane through its direct interaction with phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)). It has also been reported that the interaction between EXOC7 and PI(4,5)P(2) is highly essential for the docking and fusion of post-Golgi secretory vesicles.

Features and Benefits

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General description

EXOC7 (Exocyst complex component 7) is a major component of a multiprotein, octameric complex, exocyst. It is localized in the active site of active exocytosis.

Immunogen

Peptide with sequence C-DNIKNDPDKEYN from the internal region of the protein sequence according to NP_001013861.1; NP_056034.2.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.