ANTI-DUSP1

Not available outside of the UK & Ireland.

Application

Anti-DUSP1 antibody produced in goat has been used for Western blotting.

Biochem/physiol Actions

Dual specificity phosphatase 1 (DUSP1) modulates the activity of mitogen-activated protein kinase (MAPK). It targets and dephosphorylates extracellular signal-regulated kinases 1 and 2 (ERK 1/2). During cellular responses to oxidative stress, the activity of DUSP1 is regulated by p53. Overexpression of the protein has been associated with various tumors.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Dual specificity phosphatase 1 (DUSP1) is a protein phosphatase. The gene encoding it is localized on human chromosome 5q35.1.

Immunogen

Peptide with sequence SYLQSPITTSPSC from the C Terminus of the protein sequence according to NP_004408.1.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.