Anti-ASMTL antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

ASMTL (Acetylserotonin O-methyltransferase-like) is a novel gene located in the pseudoautosomal region (PAR1) of the human X and Y chromosomes. It has a bipartite structure expressed in pancreas, placenta, colon, fibroblast and fetal brain tissues. Its C-terminal end possesses structural homology with N-acetylserotonin O-methyltransferase and N-terminal end has the similarity with multicopy associated filamentation (maf) protein of Bacillus subtilis and to orfE of Escherichia coli. ASMTL encodes the enzyme catalysing the last step in the synthesis of melatonin.

Immunogen

ASMTL (AAH02508.1, 1 a.a. ~ 621 a.a) full-length human protein.SequenceMVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSKVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP

Physical form

Solution in phosphate buffered saline, pH 7.4