Anti-Ndp

Not available outside of the UK & Ireland.

General description

This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy. (provided by RefSeq)

Immunogen

NDP (NP_000257.1, 1 a.a. ~ 133 a.a) full-length human protein.SequenceMRKHVLAASFSMLSLLVIMGDTDSKTDSSFIMDSDPRRCMRHHYVDSISHPLYKCSSKMVLLARCEGHCSQASRSEPLVSFSTVLKQPFRSSCHCCRPQTSKLKALRLRCSGGMRLTATYRYILSCHCEECNS

Physical form

Solution in phosphate buffered saline, pH 7.4