Monoclonal Anti-TNFRSF6B antibody produced in mouse, clone 1F1, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5′ UTR, have been observed for this gene. (provided by RefSeq)

Immunogen

TNFRSF6B (NP_116563, 32 a.a. ~ 141 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAP

Physical form

Solution in phosphate buffered saline, pH 7.4