Monoclonal Anti-NKX6-1 antibody produced in mouse, clone 1A7, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM

Immunogen

NKX6-1 (NP_006159, 191 a.a. ~ 275 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequencePKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGM

Physical form

Solution in phosphate buffered saline, pH 7.4