Monoclonal Anti-ICT1, (C-terminal) antibody produced in mouse, clone 6F8, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells. (provided by RefSeq)

Immunogen

ICT1 (NP_001536, 107 a.a. ~ 206 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceTAEWIAEPVRQKIAITHKNKINRLGELILTSESSRYQFRNLADCLQKIRDMITEASQTPKEPTKEDVKLHRIRIENMNRERLRQKRIHSAVKTSRRVDMD

Physical form

Solution in phosphate buffered saline, pH 7.4