Monoclonal Anti-ADRA1A, (N-terminal) antibody produced in mouse, clone 5G8, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. (provided by RefSeq)

Immunogen

ADRA1A (NP_150646, 1 a.a. ~ 27 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceMVFLSGNASDSSNCTQPPAPVNISKAI

Physical form

Solution in phosphate buffered saline, pH 7.4