Anti-Fem1A

Not available outside of the UK & Ireland.

Biochem/physiol Actions

FEM1A (fem-1 homolog A) protein is involved in the regulation of stem-loop binding protein, that is associated with mRNA cleavage, translation and degradation. FEM1A is involved in anti-inflammatory signaling by interacting with prostaglandin E2 subtype E4 receptors. FEM1A is associated with the pathogenesis of polycystic ovary syndrome. Studies show that FEM1A gene is downegulated in rhabdomyosarcoma.

Features and Benefits

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Immunogen

FEM1A (NP_061178.1, 1 a.a. ~ 669 a.a) full-length human protein.SequenceMDLRTAVYNAARDGKLQLLQKLLSGRSREELDELTGEVAGGGTPLLIAARYGHLDVVEYLVDRCGASVEAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTTRTNSTPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQVNRRSAKGNTALHDCAESGSLEILQLLLGCKARMERDGYGMTPLLAASVTGHTNIVEYLIQEQPGQEQVAGGEAQPGLPQEDPSTSQGCAQPQGAPCCSSSPEEPLNGESYESCCPTSREAAVEALELLGATYVDKKRDLLGALKHWRRAMELRHQGGEYLPKPEPPQLVLAYDYSREVNTTEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQSNLEPLSPMTASSFLSFAELFSYVLQDRAAKGSLGTQIGFADLMGVLTKGVREVERALQLPREPGDSAQFTKALAIILHLLYLLEKVECTPSQEHLKHQTVYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLLDCGADPDSRDFDNNTPLHIAAQNNCPAIMNALIEAGAHMDATNAFKKTAYELLDEKLLARGTMQPFNYVTLQCLAARALDKNKIPYKGFIPEDLEAFIELH

Physical form

Solution in phosphate buffered saline, pH 7.4