Anti-ALOX5AP (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Immunogen

ALOX5AP (NP_001620, 91-127)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human ALOX5AP.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.