Anti-MD2 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

MD2 cooperates with toll-like receptor 4 (TLR4)on the cell surface in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. This protein enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.

Immunogen

MD2 (NP_056179, )This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MD2.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.