Anti-CYP26A1 (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Cytochrome P450 family 26 subfamily A member 1 (CYP26A1) is a retinoic acid (RA) degrading enzyme. It plays a vital role in RA metabolism. CYP26A1 has an essential role in the correct anteroposterior patterning and the generation of migratory cranial neural crest cells in the developing mammalian brain. Mutations in the gene is associated with the pathogenesis of optic nerve aplasia (ONA).

Disclaimer

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General description

Cytochrome P450 family 26 subfamily A member 1 (CYP26A1) is encoded by the gene mapped to human chromosome 10q23.33.

Immunogen

CYP26A1 (NP_000774, 123-157)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CYP26A1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.