ANTI-BCCIP (C-TERM)

Not available outside of the UK & Ireland.

General description

BCCIP was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21.

Immunogen

BCCIP (NP_510869, 263-302)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BCCIP.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.