Anti-PYGM (center) antibody produced in rabbit, Ig fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

PYGM catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of glycogen storage disease type 5 (GSD5), also known as McArdle disease. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.

Immunogen

PYGM (NP_005600, 522-556)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PYGM.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.