Anti-IGFBP3 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.

Immunogen

IGFBP3 (NP_036720, 168-203)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of rat IGFBP3.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.