Anti-URM1 (N-term) antibody produced in rabbit, Ig fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

Following the discovery of protein modification by the small, highly conserved ubiquitin polypeptide, a number of distinct ubiquitin-like proteins (Ubls) have been found to function as protein modifiers as well. These Ubls, which include SUMO, ISG15, Nedd8, and Atg8, function as critical regulators of many cellular processes, including transcription, DNA repair, signal transduction, autophagy, and cell-cycle control. A growing body of data also implicates the dysregulation of Ubl-substrate modification and mutations in the Ubl-conjugation machinery in the etiology and progression of a number of human diseases. URM1 is a ubiquitin-like modifier protein.

Immunogen

URM1 (NP_112176, 23-60)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human URM1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.