Anti-PSMA5 (N-term) antibody produced in rabbit, Ig fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PMA5 is a member of the peptidase T1A family, that is a 20S core alpha subunit.

Immunogen

PSMA5 (NP_002781, 1-30)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PSMA5.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.