Anti-Sodium Channel NaV1.9 antibody produced in rabbit, affinity isolated antibody, lyophilized powder

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Sodium Channel NaV1.9 participates in pain at the time of inflammation. Downregulation of Nav1.9 is observed in Hirschsprung′s disease.

Disclaimer

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General description

Sodium Channel NaV1.9 is a threshold channel, that is expressed in dorsal root ganglion neurons , peripheral nociceptive neurons and visceral afferents. It is also called as SNS and NaN. It is encoded by SCN11A (sodium voltage-gated channel subunit 11) and is located on human chromosome 3p22.

Immunogen

peptide CNGDLSSLDVAKVKVHND corresponding to residues 1748-1765 of rat Na_v1.9. This sequence has 15/18 residues identical in mouse and 14/18 residues identical in human.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, with 1% bovine serum albumin, and 0.05% sodium azide.