Anti-APH1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

APH1 (anterior pharynx defective-1) participates in the secretase like activity. Throughout the embryonic development, APH1 participates in presenilin dependent function.

Disclaimer

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General description

APH1 (anterior pharynx defective-1) is a component of γ-secretase complex. It is located on chromosome 1q21. It has 2 unique isoforms such as APH1a, located on chromosome 1 and APH1b, located on chromosome 15 (3).

Immunogen

a 18 amino acid peptide from near the center of human APH1.

Linkage

The action of this antibody can be blocked using blocking peptide SBP4003.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide