Anti-TLR4 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Toll-like receptors (TLRs) are transmembrane receptors expressed on the surface of immune and non-immune cells. There are at least 13 different TLRs identified that mediate signalling pathways contributing to acute inflammatory processes during tissue damage and bacterial infections TLR2 is highly inducible by numerous inflammatory mediators resulting in translocation of transcription factor NF-κB-mediated proinflammatory cytokines and immune responses

Immunogen

a peptide corresponding to 15 amino acids near the amino-terminus of human TLR4.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3141.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide