Not available outside of the UK & Ireland.
Application
Immunofluorescence Analysis: a previous lot of this antibody was used by an independent laboratory in IF. (Yang, J.W., et al. (2007). PNAS. 104(50):20055–20060.)
This Anti-Potassium Channel Kv1.2 Antibody, clone K14/16 is validated for use in IH, WB, IF for the detection of Potassium Channel Kv1.2.
General description
Potassium channel Kv1.2 is one of many different types of potassium channels in the cell. The Kv family of potassium channels seem to have a conserved homotetramer formation consisting of four voltage sensors and one pore domain. Kv1.2 cooperates with cortactin (an actin cytoskeleton-binding protein) and together they may have a part in the regulation of the ionic current.
Immunogen
Recombinant protein corresponding to rat Kv1.2.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Quality
Evaluated by Western Blot in rat brain membrane tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Kv1.2 on 10 µg of rat brain membrane tissue lysate.
Target description
~ 65 kDa observed
This product has met the following criteria to qualify for the following awards: