Anti-Histamine antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Anti-Histamine antibody produced in rabbit has been used:in immunohistochemistryto test immunohistochemical reactions of Pseudophoxinus antalyae digestive system tissuesin immunocytochemical assaysin immunofluorescence assays

Biochem/physiol Actions

Histamine, (2-(4-Imidazolyl)ethylamine) mediates a variety of physiological activities including inflammation, gastric acid secretion and smooth muscle contraction. It is also implicated in modulation of cell growth and differentiation, during embryogenesis, and tumor growth and in the suppression of mitogen-induced lymphocyte proliferation. In the central nervous system (CNS), histamine acts as a neurotransmitter/ neuromodulator of various brain activities.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Histamine, (2-(4-Imidazolyl)ethylamine), is a widely distributed substance in peripheral tissues. Histamine is localized in mast cells, neuronal cells and neuroendocrine cells of the gastric tract. It is also expressed in lungs, kidney, in cerebrovascular endothelial cells and throughout the peripheral nervous system.

Immunogen

histamine conjugated to succinylated KLH

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide

Specificity

The product specifically stains histamine-containing cells in paraformaldehyde/carbodiimide-fixed or paraformaldehyde-fixed, paraffin-embedded sections of rat stomach (endocrine cells and mast cells).