Anti-TCOF1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Anti-TCOF1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Treacle protein is a protein encoded by the TCOF1 gene in humans. Mutation in this gene is associated with Treacher Collins syndrome (TCS), the most common and well-known mandibulofacial dysostosis. It is an autosomal dominant craniofacial disorder characterised by midface hypoplasia, micrognathia, downslanting palpebral fissures, eyelid colobomata and ear deformities.

Immunogen

Recombinant treacle

Immunogen Sequence: GI # 4507411, sequence 4-193

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.