Anti-STAT6 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Anti-STAT6 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

STAT6 is a human gene and is a member of the STAT family of transcription factors. It is mapped to human chromosome band 12q13. STAT6 has the same functional domain for both receptor coupling and dimerization. It is highly expressed in comparison with the other STAT proteins. STAT-6 silencing results in the reduction of HeLa cell programmed death and the expression of several important key factors related to programmed cell death. It is a highly sensitive and specific marker of solitary fibrous tumor (SFT). It can also be helpful in distinguishing tumor type from histologic mimics.

Immunogen

Immunogen Sequence: GI # 23397678, sequence 61-275

Recombinant signal transducer and activator of transcription 6

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.