Anti-Glial Cell-derived Neurotrophic Factor (GDNF) antibody produced in goat, IgG fraction of antiserum, lyophilized powder

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Glial cell-derived neurotrophic factor is a potent neurotrophic factor that is important for the maintenance, regeneration and survival of specific neuronal cells including autonomic neurons, motoneurons, noradrenergic and seotonergic neurons. Additionally, it promotes the invasion and metastatic behavior of certain types of cancers by activating ERK, p38, JNK and AP-1 mediated cell signaling.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The antibody neutralizes the biological activity of recombinant human GDNF.

Immunogen

recombinant human GDNF expressed in Escherichia coli.

Physical form

Lyophilized from a 0.2 µm filtered solution in phosphate buffered saline

Preparation Note

Purified using protein G.