Anti-Granulocyte Colony Stimulating Factor antibody produced in goat, affinity isolated antibody, lyophilized powder

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The main functions of G-CSF include the generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow.

Immunogen

purified, recombinant mouse granulocyte colony stimulating factor, expressed in E. coli.

Physical form

Lyophilized from a 0.2 µm filtered solution in phosphate buffered saline with 5% trehalose.