Anti-GATA1 antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Anti-GATA1 antibody produced in rabbit is suitable for immunoblotting at a working dilution of 1:500 to 1:1000 and for immunohistochemistry at a working dilution of 1:100 to 1:250.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunofluorescence (1 paper)

Biochem/physiol Actions

GATA1 belongs to the GATA family of transcription factors. The encoded protein regulates erythroid development and megakaryocyte differentiation. It binds to the consensus sequence 5′-[AT]GATA[AG]-3′ within the regulatory region. Defects in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Reduced levels of GATA1 may cause Diamond-Blackfan anemia.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

synthetic peptide corresponding to residues 211-225 of human GATA1.

Physical form

solution in phosphate buffered saline, containing 0.02% sodium azide.