Anti-BRAL1

Non disponible en dehors du Royaume-Uni et de l'Irlande

Analysis Note

ControlHuman brain tissue lysate

Application

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected BRAL1 in human brain tissue.

Research CategoryNeuroscience

Anti-BRAL1 detects levels of BRAL1 proteins & has been published & validated for use in WB & IHC.

Research Sub CategoryDevelopmental Neuroscience

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Brain link protein 1 (BRAL1) is a member a superfamily consisting of several highly homologous hyaluronan and proteoglycan binding link proteins. BRAL1 is predominantly expressed in brain tissue and spinal cord. Like other members in the link-module superfamily, BRAL1 contains an immunoglobulin-like fold and two proteoglycan tandem repeats (PTRs). Its mRNA expression pattern is similar to other lectican proteoglycans, suggesting that BRAL1 may act to stabilize the binding between the extracellular matrix molecule hyaluronan and brevican. Immunostaining of mouse brain showed BRAL1 expression at P20 in the white matter of the developing cerebellum and in myelinated fiber tracts in the adult brain, suggesting that expression starts when axonal myelination occurs.

Immunogen

KLH-conjugated linear peptide corresponding to human BRAL1.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.

Antigen Affinity Purified

Quality

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected BRAL1 in 15 µg of human brain tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~36 kDa observed