Anti-moisissure

Non disponible en dehors du Royaume-Uni et de l'Irlande

Analysis Note

ControlMouse testis lysate

Application

Research Sub CategoryNeurodegenerative Diseases

Research CategoryNeuroscience

Anti-mHUMMR Antibody is an antibody against mHUMMR for use in WB.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Hypoxia up-regulated mitochondrial movement regulator (HUMMR), a novel mitochondria protein, is expressed in neurons and is markedly induced by hypoxia-inducible factor 1 α (HIF-1α). HUMMR interacts with Miro-1 and Miro-2, mitochondrial proteins that are critical for mediating mitochondrial transport. Knockdown of HUMMR or HIF-1 function in neurons exposed to hypoxia markedly reduces mitochondrial content in axons.

Immunogen

Epitope: Unknown

Linear peptide corresponding to mouse HUMMR.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blot in mouse testis lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected HUMMR on 10 µg of mouse testis lysate.

Specificity

This antibody recognizes mouse HUMMR protein

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~ 45 kDa observed. 50 kDa calculated.