Anti-UTF1

Not available outside of the UK & Ireland.

Application

Research Sub CategoryNuclear Receptors

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected UTF1 in mouse kidney and rat liver tissue.

Anti-UTF1 Antibody is an antibody against UTF1 for use in Western Blotting and Immunohistochemistry.

Research CategoryEpigenetics & Nuclear Function

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Undifferentiated embryonic cell transcription factor 1 is a nucleus protein encoded by the UTF1 gene in human and functions as a transcriptional coactivator of ATF2. UTF1 is reported to interact with the ATF-2 metal binding motif via the leucine zipper motif within its conserved domain 2 (CD2) and both CD1 & CD2 of UTF1 and also independently mediates association with TATA-binding protein-containing complex. (PMID 9749258)

Immunogen

KLH-conjugated linear peptide corresponding to human UTF1 near N-terminus.

Epitope: Near N-terminus

Linkage

Replaces: AB3383

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Affinity

Quality

Evaluated by Western Blotting in mouse embryonic stem cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected UTF1 in 10 µg of mouse embryonic stem cell lysate.

Specificity

Other homologies: mouse, rat 95%.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~48 kDa observed. UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells (Okuda, A., et al. (1998). EMBO. 17(7):2019–2032).