Anti-Myosin X

Not available outside of the UK & Ireland.

Analysis Note

ControlHuman head/neck lysate.

Application

Detect Myosin X using this Anti-Myosin X Antibody validated for use in WB.

General description

Myosins are a superfamily of molecular motor proteins found in eukaryotic cells. Motor proteins are involved in muscular contraction, cytokinesis, short-range membrane/vesicle transport and a host of other cellular processes. The myosins are responsible for actin-based motility by using the energy of ATP hydrolysis to generate force and movement along actin filaments. There are many isoforms of myosin of which some have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. Myosin X belongs to a group of myosin isoforms known as unconventional myosins that participate in cellular processes ranging from membrane trafficking to signaling and cell motility. Myosin X is concentrated at the tips of filopodia and Myosin X rich regions travel forward and backward along filopods, (Berg, 2002). It also appears that Myosin X functions in actual filopodia formation, (Bohil, 2006).

Immunogen

Epitope: a.a. 936-953

KLH-conjugated synthetic peptide to amino acids 936-953 of human Myosin X.

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

Quality

Evaluated on a representative lot by Western blot on human head/neck lysate using Anti-Myosin X.

Specificity

Predicted to cross react with mouse and rat based on 100% sequence homology. Reactivity with other species has not been tested.

Cat. No. AB1094 recognizes human Myosin X.

Storage and Stability

Maintain at -20°C for up to 1 year from date of receipt.
Upon arrival, aliquot into usable quantities to avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Target description

~ 108 kDa