Anti-ADAMTS-3, Propeptide Region antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Not available outside of the UK & Ireland.

Application

Rabbit Anti-ADAMTS-3, Propeptide Region can be used for western blot assays at a dilution of 1:1,000.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

By immunoblotting against the reduced protein, the antibody identifies the zymogen form at 130-140 kDa, activated forms at 94-105 kDa (major bands), and breakdown products at 50 kDa, 34 kDa in cell culture media and lysates.

ADAMTS-3 belongs to the ADAM (A Disintegrin And Metalloproteinase) family and has thrombospondin (TS) repeats. Studies have suggested that ADAMTS-3 is preferably expressed in the cartilages and has procollagen II N-propeptidase functions. Rabbit Anti-ADAMTS-3, Propeptide Region antibody binds to propeptide region of human ADAMTS-3.

Immunogen

synthetic peptide corresponding to the propeptide domain of human ADAMTS-3.

Physical form

Solution in phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.