Récepteur Anti-phospho - AMPA,sous - unité GluR1 (pSer831) anticorps produit en lapin, environ 1 mg/mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸³¹) antibody is suitable for use in direct ELISA, immunohistochemistry, immunoblot and immunoprecipitation. The antibody may also be used for western blot (1:1,000 using rat hippocampal homogenate).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

GluR1 subunits of AMPA receptors are membrane proteins that regulate synaptic plasticity of the central nervous system. This receptor has also been implicated in spatial memory retention. Phosphorylation of serine 831 in GluR1 subunit of the AMPA receptor modulates long-term potentiation in neuronal synapses. Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸³¹) antibody is specific for the GluR1 subunit (phosphorylated on serine 831) of the AMPA receptor in rats and humans.

AMPA is a transmembrane receptor for glutamate that regulates synapsis in the central nervous system. It is composed of 4 types of subunits, GluR1, 2, 3, 4.

Immunogen

The GluR1 sequence is conserved among species and has partial homology to VGLUT2.

synthetic phosphopeptide corresponding to a region near serine 831 of rat glutamate receptor subunit GluR1.

Physical form

Solution in 10 mM HEPES buffer, pH 7.5, containing 150 mM NaCl, 100 µg/ml BSA and 50% glycerol.