Anti-Amyloid Peptide beta, Cleavage Site 42 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Rabbit anti-Aβ42 is suitable for use in immunoblot, immunohistochemistry, immunoprecipitation, RIA, ELISA and dot blot applications.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunohistochemistry (1 paper)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Proteolytic cleavage of the amyloid precursor protein (APP) produces the small fragment amyloid β peptide. Cleavage of APP occurs mostly at residue 40 but to a lesser extent residue 42. Aggregates of amyloid β peptide are found deposited in the brains of Alzheimer′s patients.

Rabbit anti-amyloid peptide β, cleavage site 42 (Aβ42) antibody binds to human, mouse and rat Aβ42.

Immunogen

synthetic peptide of approximately 10 amino acid residues at the C-terminus of Aβ42.

Physical form

Solution in phosphate buffer, pH 7.4, containing approximately 25 µg of antibody.