Anti-Albumin antibody produced in rabbit, IgG fraction of antiserum

Not available outside of the UK & Ireland.

Application

Anti-Albumin antibody produced in rabbit has been used in:immunocytochemistry immunoassay of amino-terminal fragments(ATF)-human serum albumin (HSA)canstatin (Can) - human serum albumin (HSA)enzyme-linked immunosorbent assay (ELISA)

Biochem/physiol Actions

Three major functions for serum albumin have been proposed: maintenance of osmotic pressure, transportation of a variety of substances and an endogenous source of amino acids. The primary sites of albumin degradation are not known, but the protein can be metabolized by almost every organ in the body. Determination of serum albumin levels is a widely used screening test in clinical medicine. A decrease in serum albumin levels may indicate disease states such as malnutrition, cirrhosis, nephrotic syndrome, diabetes, gastrointestinal and hepatic diseases, thermal burns and pulmonary disease. High levels of albumin are associated with dehydration. Albumin turnover is seen in infants with iron deficiency anemia. Advanced liver disease is associated with oxidative damage of albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Albumin is the most abundant plasma protein in humans.

Albumin, the major protein produced by liver cells, represents more than half of the total protein content of human serum. Many other body fluids also contain albumin.

Immunogen

purified human albumin

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide

Specificity

Rabbit polyclonal anti-Albumin antibody reacts with human serum and human albumin.