Non disponible en dehors du Royaume-Uni et de l'Irlande
General description
Full-length, recombinant, human phosphodiesterase 3B (accession no. AY459346) fused at the N-terminus to a His Tag™ sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. An important component of insulin and cAMP-dependent signaling. Supplied as a partially purified preparation.
Legal Information
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol.538, 39.Kitamura, T., et al. 1999. Mol. Cell. Biol.19, 6286.Degerman, E., et al. 1997. J. Biol. Chem.272, 6823.
Packaging
10 u in Plastic ampoule
Physical form
In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
Reconstitution
Following initial thaw, aliquot and freeze (-70°C).
Unit Definition
One unit is defined as the amount of enzyme that will convert 1 pmole cAMP to AMP per min at pH 7.5, 30°C.
Warning
Toxicity: Standard Handling (A)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :