Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Cell permeable, potent and specific irreversible inhibitor of the proteasome. Novel mechanism of action. Blocks chymotrypsin-like, trypsin like and PGPH activities of the proteasome. Regulates antigen presentation at non-toxic doses. Displays in vivo anti-inflammatory activity in mouse ear inflammation assay and in vitro NF-kB inhibition. The product is not sterile.
Biochem/physiol Actions
Inhibitor Type: Protease Inhibitors
Protein Target: RPS27A
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage and Stability
Store at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :