NSC 663284, >=98% (HPLC), solid

Code: N7537-5MG D2-231

Not available outside of the UK & Ireland.

Application

NSC 663284 has been used as a cell division cycle 25(CDC25) inhibitor to study its effects on the level of kizuna (kiz) dephosphorylation. It has also been used a...


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Your Price
$273.28 5MG
REQUEST

Not available outside of the UK & Ireland.

Application

NSC 663284 has been used as a cell division cycle 25(CDC25) inhibitor to study its effects on the level of kizuna (kiz) dephosphorylation. It has also been used as a control in horseradish peroxidase/phenol red based assay and resazurin-based redox assay.

Biochem/physiol Actions

Potent, irreversible, cell permeable and mixed competitive CDC25 phosphatase family inhibitor

NSC 663284 is a quinolinediones, which is involved in the inhibition of cell cycle progression at both G1 and G2/M phase. It is also involved in inhibiting the dephosphorylation and activation of cyclin-dependent kinases (Cdks) in vitro and in vivo. NSC 663284 stops the proliferation of various tumor cell lines.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorred
formsolid
Gene Informationhuman ... CDC25B(994), DUSP3(1845), PTPN1(5770)
InChI keyBMKPVDQDJQWBPD-UHFFFAOYSA-N
InChI1S/C15H16ClN3O3/c16-11-13(18-4-5-19-6-8-22-9-7-19)15(21)12-10(14(11)20)2-1-3-17-12/h1-3,18H,4-9H2
Quality Level100
SMILES stringClC1=C(NCCN2CCOCC2)C(=O)c3ncccc3C1=O
solubilityH2O: insoluble, DMSO: ≥10 mg/mL
storage conditionprotect from light
storage temp.2-8°C
Cas Number383907-43-5
This product has met the following criteria to qualify for the following awards:



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