FQI1, >=98% (HPLC)

Code: SML0413-25MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

FQI1 inhibits the DNA-binding activity of LSF, a ubiquitous transcription factor that is up regulated in many hepatocellular carcinomas (HCC). FQI1 in...


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$355.85 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

FQI1 inhibits the DNA-binding activity of LSF, a ubiquitous transcription factor that is up regulated in many hepatocellular carcinomas (HCC). FQI1 inhibits LSF-dependent luciferase reporter expression, blocks proliferation in cancer cell lines, and induces apoptosis in liver cancer cells but is not toxic to primary hepatocytes. FQI1 also inhibits tumor growth in a mouse HCC xenograft model.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyYKSYGLXHLSPWLB-UHFFFAOYSA-N
InChI1S/C18H17NO4/c1-2-21-15-6-4-3-5-11(15)12-8-18(20)19-14-9-17-16(7-13(12)14)22-10-23-17/h3-7,9,12H,2,8,10H2,1H3,(H,19,20)
Quality Level100
SMILES stringO=C1CC(C2=CC=CC=C2OCC)C3=CC4=C(OCO4)C=C3N1
solubilityDMSO: 10 mg/mL (clear solution)
storage temp.2-8°C
Cas Number599151-35-6
Hazard Class6.1
Un Number2811
Pack Group3
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